银河

洪强，博士，副教授，硕士生导师，银河 基础医学院组织学与胚胎学教研室副主任，安徽省医药生物技术协会副秘书长。

2021.06 - 至今，      银河 ，银河 组织胚胎学教研室，校聘副教授

2019.04 - 2021.05，深圳市东阳光实业发展有限公司，生物药研究所

2011.09 - 2018.12，武汉大学，细胞生物学，博士

2007.09 - 2011.06，黄山银河 ，生物技术，学士

1.安徽省重点实验室开放基金项目，AHFS2025ZD01，人工智能标准化脐带间充质干细胞对放射性卵巢损伤的治疗作用及其机制研究，2026/01-2027/01；

2.国家自然科学基金青年项目，82201804，泛素连接酶TRIM24介导SOX3蛋白降解促进PCOS高雄激素血症发生的机制研究，2023/01-2025/12；

3.安徽省自然科学基金青年项目，2208085QH235，干细胞因子Sox3调控颗粒细胞增殖和卵泡发育的作用与机制研究，2022/01-2023/12；

4.安徽高校自然科学研究重点项目，KJ2021A0217，转录因子Sox3调控PI3K/AKT/Bcl-2信号通路抑制卵巢颗粒细胞凋亡的机制研究，2022/01-2023/12；

5.银河 人才引进科研启动基金，0111029202；

1. Cong Li; Anqi Zhu; Wenhui Shi; Yifei Wang; Rongjia Zhou; Yanghua Tian*; Zhimin Zhai*; Qiang Hong*. A novel chimeric RNA RPGR-EEF1A1 enhances autophagy by interaction with the small GTPase RAB37 in a GTP-dependent manner. Genes & Diseases, 2026, 102063.

2. Fangnan Wu, Jieru Liu, Yuanyang Qing, Zhenxin Sun, Zhen Tian, Chen Chen, Kexin Liu, Shuai Lin, Qiang Hong*, Yijun Fan*, Yuanhua Chen*. Zearalenone disrupts the placental barrier via integrated stress response activation in mice and human trophoblast cells. Journal of Agricultural and Food Chemistry, 2026, 74(10):8671-8686.

3. Cong Li, Xue Liang, Siqi Gong, Mengmeng Fan, Yanghua Tian*, Qiang Hong*, Zhimin Zhai*. Integrative analysis of proteomics and metabolomics reveals amino acid metabolism disorder in adriamycin-resistant acute myeloid leukemia cells. Scientific Reports, 2026, 16(1):4902.

4. Rui Cai, Cong Li, Wenhui Shi, Fenfen Xie, Mengmeng Fan, Hao Zhang, Zhuang Liu, Yuanhua Chen, Qiang Hong*. SOX3 facilitates granulosa cell proliferation and suppresses cell apoptosis through modulating PI3K/AKT pathway by targeting SPP1. Cellular and Molecular Life Sciences, 2025, 82(1):266.

5. Wenxiu Chen; Hongyan Zhang; Bao Guo; Yumei Tao; Junhui Zhang; Jiayi Wang; Guangyi Chen; Mengting Cheng; Qiang Hong*; Yunxia Cao*; Fenfen Xie*. Melatonin refines ovarian mitochondrial dysfunction in PCOS by regulating the circadian rhythm gene Clock. Cellular and Molecular Life Sciences, 2025, 82(1):104.

6. Guangyi Chen; Junhui Zhang; Jiayi Wang; Wenxiu Chen; Haoran Li; Haoran Su; Shaoyi Dai; Yumei Tao; Yunxia Cao*; Qiang Hong*; Fenfen Xie*. Regulation of alternative splicing of retinol metabolism in lipid abnormality of PCOS liver by Cyp4a32 and Hsd17b6. Genomics, 2025, 117(6):111136.

7. Cong Li; Rui Cai; Wenhui Shi; Hao Zhang; Zhuang Liu; Fenfen Xie*; Yuanhua Chen*; Qiang Hong*. Comparative tranome analysis of ovaries and testes reveals sex-biased genes and pathways in zebrafish. Gene, 2024, 901: 148176

8. Junhui Zhang, Hongyan Zhang, Bao Guo, Jun Yang, Renxiang Yu, Wenxiu Chen, Muxin Zhai, Yuhan Cao, Yajing Liu, Qiang Hong*, Fenfen Xie*. Melatonin attenuates hepatic oxidative stress by regulating the P62/LC3 autophagy pathway in PCOS. Endocrine Connections, 2024, 13(12):e240303.

9. Qiang Hong^#; Mengmeng Fan^#; Rui Cai; Wenhui Shi; Fenfen Xie; Yuanhua Chen; Cong Li. SOX4 regulates proliferation and apoptosis of human ovarian granulosa-[like] tumor cell line KGN through the Hippo pathway. Biochemical and Biophysical Research Communications, 2024, 705:149738

10. Qiang Hong^#, Cong Li^#, Ruhong Ying, Heming Lin, Jingqiu Li, Yu Zhao, Hanhua Cheng, Rongjia Zhou. Loss-of-function of sox3 causes follicle development retardation and reduces fecundity in zebrafish. Protein Cell, 2019, 10(5): 347–364.

1. 张旭辉,宁维瑜,何亮亮,罗显麟,洪强,赵光辉,颜青青,唐锐华,李晓平,郭林峰,陈超,叶群瑞,陈小锋,李文佳。构建体及其应用, 2020-6-16, 中国,ZL 202010550858.0