银河

朱勇，银河 病理生理学教研室副教授，安徽省高校优秀青年。2019六月毕业于中国科学技术大学肿瘤分子病理学实验室，当年七月即作为“东南人才”计划四类人才引进进入银河 病理生理学教研室承担教学科研工作。主要从事肿瘤环境分子病理及代谢性脂肪肝病的表观遗传调控机制研究。相关工作围绕在探索纳米材料暴露对乳腺癌转移的效应和分子机制，研究成果以第一作者和通讯作者发表在Nature Nanotechnology（引用 150多次，2026）和ACS Nano （2024）。此外，我们还围绕肿瘤及代谢性脂肪肝病的分子病理展开了一系列研究，研究成果以通讯作者发表在Journal of Experimental & Clinical Cancer Research（2024）和Advanced science（2024）。

教育经历

2013.09 - 2019.06   中国科学技术大学，细胞生物学，博士研究生，导师：朱涛

2008.09 - 2012.06   安徽大学，生物技术，本科

工作经历

2019.07-2024.12     银河 , 银河 ，校聘副教授,“东南人才”四类，硕士生导师

2025.01-至今           银河 , 银河 ，副教授,“东南人才”四类，硕士生导师

1. 国家自然科学基金青年项目，82203866，长非编码RNA FAM225B调控的LYN mRNA稳定性在促进乳腺肿瘤干性中的功能和机制研究，2023/01-2025/12，30 万，结题，主持;

2. 安徽省高校科学基金优青项目，2024AH030020，PM2.5 致瘤效应与肿瘤微环境， 2025/01-2027/12，50 万，在研，主持;

3. 安徽省自然科学基金青年项目，2008085QH411，长非编RNA LINC00467调控乳腺癌肿瘤表型的机制研究， 2020/07-2022/06，10 万，结题，主持;

4. 银河 基础与临床合作研究提升计划，2020xkjT013，全身麻醉药通过巨噬细胞来源的长非编码RNA LINC00662 调控乳腺癌转移效应的研究，2021/01-2023/12，20 万，结题，主持。

1. Ding, K.#, Zhu, Y.#, Yan, L.#, Zhu, L., Zhang, T., Zhang, R., Li, Q., Xie, B., Ding, L., Shang, L., Wang, Y., Xu, P., Zhu, T.*, Chen, C.*, & Zhu, Y.* (2024). Multiwalled Carbon Nanotubes-Reprogrammed Macrophages Facilitate Breast Cancer Metastasis via NBR2/TBX1 Axis. ACS nano, 10.1021/acsnano.3c11651. (期刊论文)

2. Ding, L.#, Jiang, H.#, Li, Q.#, Li, Q., Zhang, T. T., Shang, L., Xie, B., Zhu, Y., Ding, K., Shi, X.*, Zhu, T.*, & Zhu, Y*. (2024). Ropivacaine as a novel AKT1 specific inhibitor regulates the stemness of breast cancer. Journal of experimental & clinical cancer research : CR, 43(1), 90. (期刊论文)

3. Zhu, Y. #, Shang, L. #, Tang, Y. #, Li, Q., Ding, L., Wang, Y., Zhang, T., Xie, B., Ma, J., Li, X., Chen, S., Yi, X., Peng, J., Liang, Y., He, A., Yan, H., Zhu, H. *, Zhang, B. *, & Zhu, Y *. (2024). Genome-Wide Profiling of H3K27ac Identifies TDO2 as a Pivotal Therapeutic Target in Metabolic Associated Steatohepatitis Liver Disease. Advanced science (Weinheim, Baden-Wurttemberg, Germany), e2404224. (期刊论文)

4. Zhang, R. #, Wang, Z. #, Wang, H. #, Li, L., Dong, L., Ding, L., Li, Q., Zhu, L., Zhang, T., Zhu, Y. *, & Ding, K. * (2024). CTHRC1 is associated with BRAF(V600E) mutation and correlates with prognosis, immune cell infiltration, and drug resistance in colon cancer, thyroid cancer, and melanoma. Biomolecules & biomedicine, 25(1), 42–61. (期刊论文)

5. Zhu, L., Zhu, H., Zhang, Z., Xu, F., Zhu, Y. ^*, & Ding, K. ^* (2025). A Novel Prognostic Model of Endometrial Cancer Based on Inflammation and Lipid Metabolism Genes. Genetic testing and molecular biomarkers, 29(8), 216–231. (期刊论文)

6. Lu, X.#, Zhu, Y.#, Bai, R., Wu, Z., Qian, W., Yang, L., Cai, R., Yan, H., Li, T., Pandey, V., Liu, Y., Lobie, P. E., Chen, C.*, & Zhu, T*. (2019). Long-term pulmonary exposure to multi-walled carbon nanotubes promotes breast cancer metastatic cascades. Nature nanotechnology, 14(7), 719–727. (期刊论文)

7. Zhang, Y.^#, Sun, Y.^#, Ding, L., Shi, W., Ding, K., & Zhu, Y^*. (2021). Long Non-Coding RNA LINC00467 Correlates to Poor Prognosis and Aggressiveness of Breast Cancer. Frontiers in oncology, 11, 643394. (期刊论文)

8. Zhu, Y.^#, Zhang, R.^#, Zhang, Y., Cheng, X., Li, L., Wu, Z.^*, & Ding, K^*. (2021). NUDT21 Promotes Tumor Growth and Metastasis Through Modulating SGPP2 in Human Gastric Cancer. Frontiers in oncology, 11, 670353. (期刊论文)

9. Zhu, Y., Yang, L., Chong, Q. Y., Yan, H., Zhang, W., Qian, W., Tan, S., Wu, Z., Lobie, P. E.*, & Zhu, T*. (2019). Long noncoding RNA Linc00460 promotes breast cancer progression by regulating the miR-489-5p/FGF7/AKT axis. Cancer management and research, 11, 5983–6001. (期刊论文)

10. Yuan, H.#, Yan, L.#, Wu, M., Shang, Y., Guo, Q., Ma, X., Zhang, X., Zhu, Y., Wu, Z., Lobie, P. E.*, & Zhu, T*. (2022). Analysis of the Estrogen Receptor-Associated LncRNA Landscape Identifies a Role for ERLC1 in Breast Cancer Progression. Cancer research, 82(3), 391–405. (期刊论文)

11. Yang, L.#, Wang, M.#, Wang, Y., Zhu, Y., Wang, J., Wu, M., Guo, Q., Han, X., Pandey, V., Wu, Z., Lobie, P. E.,* & Zhu, T*. (2024). LINC00460-FUS-MYC feedback loop drives breast cancer metastasis and doxorubicin resistance. Oncogene, 10.1038/s41388-024-02972-y. (期刊论文)

12. Tan, S.#, Li, H.#, Zhang, W.#, Shao, Y., Liu, Y., Guan, H., Wu, J., Kang, Y., Zhao, J., Yu, Q., Gu, Y., Ding, K., Zhang, M., Qian, W., Zhu, Y., Cai, H., Chen, C., Lobie, P. E., Zhao, X.*, Sun, J.*, Zhu, T*. (2018). NUDT21 negatively regulates PSMB2 and CXXC5 by alternative polyadenylation and contributes to hepatocellular carcinoma suppression. Oncogene, 37(35), 4887–4900. (期刊论文)